Successful implantation of bioartificial vaginas

Publié le : 18 April 2014

 On Friday, 11 April 2014, Mexican and American scientists published the results of their work involving the implantation of laboratory-produced vaginas into young girls suffering from vaginal aplasia (born without a vagina).

"This is the first time we have succeeded in creating an entire, previously non-existent organ", announced Anthony Atala, Director of the Wake Forest Institute for Regenerative Medicine, who heads up the scientific team. The vaginas, which were implanted into four young girls between 13 and 18 years of age, were produced from vulvar cells (samples collected from the patients) and muscle cells.

1 woman out of 4,000 suffers from Mayer-Rokitansky-Küster-Hausser’s syndrome (of genetic origin), as a result of which they are born without a uterus or vagina. Surgery was performed between 2005 and 2008. Six years later, the publication announced that the implanted organs "were functioning normally" and that these young girls may even become pregnant in due course. The scientists nevertheless remain cautious and call for more extensive clinical trials.

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