Heading towards the development of a male contraceptive pill?

Publié le : 6 December 2013

 The American journal, Proceedings of the National Academy of Science, has revealed that Australian scientists at Monash University "have succeeded in making male mice infertile by blocking the function of two proteins". This research, published on 3 December, therefore represents a "new phase for the development of a male contraceptive pill".           

More specifically, the genes of male mice were modified by scientists in order to block two proteins in murine muscle cells. These proteins allow the sperm to travel through the animal’s reproductive organs. According to Sabatino Ventura, a scientist involved in the study, "the mice continued to be perfectly healthy and mated with females but no offspring were produced".           
Earlier attempts at developing a male contraceptive "focused on hormones or dysfunctional sperm production".  
The next phase for the Australian scientists is therefore to "attempt to reproduce this genetic phenomenon in chemical terms". In fact, the use of a chemical as opposed to a hormonal method would not impact upon sperm development. Research could produce a male contraceptive pill within the next decade.

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