Down syndrome: iPS cells for studying the causes of intellectual deficiency

Publié le : 4 June 2013

 A team from Wisconsin-Madison University, led by Anita Bhattacharyya, has managed for the first time to "transform skin cells of patients with Down syndrome into induced pluripotent stem cells [iPS cells]." Once these cells were obtained, they "were cultivated to transform into neurones."

Through these research findings, published in the Proceedings of the National Academy of Sciences, certain causes of the intellectual deficiency of patients with Down syndrome will be able to be confirmed. For example, the fact that in these patients, "certain neurones tend to former less connections." In concrete terms, these new cells will be able to be used "for testing different medicines targeting the symptoms of the condition.

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