Blood stem cells do not differentiate randomly

Publié le : 23 April 2013

According to research carried out by biologists of the Immunology Centre of Marseille-Luminy, the differentiation of haematopoietic stem cells does not occur in a random fashion. The specialisation of these cells, located in the bone marrow, into red corpuscles, white corpuscles and platelets, "is in fact due to a signal, a molecule called M-CSF." This signal is received by the stem cell and induces it to "react by producing the cells most suitable for dealing with a danger," for example "white corpuscles which eat microbes to fight off an infection."

According to the researchers, "it will be possible to use M-CSF to speed up the production of these cells in patients confronted by a serious risk of infection."

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